forme_membres_ICBMS Dr Gaël Tran

Dr Gaël Tran

CNRS research associate

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About Gaël

Gaël obtained his undergraduate degree from the university of Lyon (CPE Lyon & UCBL) and completed his MSc’s research under the supervision of Prof. Steven Ley (Cambridge University). He then moved to Paris to pursue doctoral studies under the supervision of Prof. Janine Cossy (ESPCI ParisTech), working in collaboration with BayerCropScience on novel synthetic routes towards densely functionalized heterocycles. After obtaining his PhD degree in 2012, he joined the group of Prof. Jonathan Ellman (Yale University) as a postdoctoral fellow, where he developed Rh-catalyzed C¬ H functionalizations of azines in collaboration with Pfizer. He then moved back to Europe to carry out further postdoctoral studies under the supervision of Prof. Clément Mazet (University of Geneva), studying both the methodological development and the mechanistic intricacies of various Ni-catalyzed processes. In 2020, he joined the SCORE team in Lyon and was appointed CNRS researcher in 2021.
Outside of the lab, Gaël enjoys playing boardgames with friends and traveling to places with interesting food.

Research interests

A major challenge in modern organic chemistry lies in the access to high-value targets from readily available building blocks in a step- and atom-economical manner. In this respect, organometallic catalysis offers unique perspectives to streamline synthesis.
Gaël’s contributions to this vibrant field revolve around the development of novel processes catalyzed by nickel, a transition metal featuring broad availability and astounding chemical properties. Beyond methodological development, Gaël’s research dedicates a large part to mechanistic studies through stoichiometric organometallic chemistry, kinetic analysis and in-situ monitoring.

Selected publications

Nickel-Catalyzed Kumada Vinylation of Enol Phosphates: A Comparative Mechanistic Study. Poisson, P.A.; Tran, G.; Mazet, C. ACS Catal. 2021, 11, 15041.

Ni-Ctalyzed Enantioselective Intermolecular Hydroamination of Branched 1,3-Diene Using Primary Aliphatic Amines. Tran, G.; Shao, W.; Mazet, C. J. Am. Chem. Soc. 2019, 141, 14814.

Base-controlled linear or branched Rh(I)-catalyzed C-H ortho-alkylation of azines without pre-activation. Tran, G.; Hesp, K.; Mascitti, V.; Ellman, J. A. Angew. Chem. Int. Ed. 2017, 56, 5899.

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