Fabien studied chemistry at the Ecole Nationale Supérieur de Chimie de Montpellier (ENSCM). He then joined the group of Dr. Bernard Langlois to develop the synthesis of new fluorinated anions and studied their properties as electrolytes for fuel cells or batteries. After obtaining his PhD degree in 2007, Fabien studied different aspects of catalysis. Thus, he joined the group of Prof. Dieter Enders (Aachen University, Germany) as a postdoctoral researcher to develop reactions based on the use of organocatalysts (mainly phosphoric acids or N-heterocyclic carbenes). Back to France as a temporary teaching and research associate at ENSICaen, his work in Prof. Annie-Claude Gaumont's group focused on the use of abundant and low toxic metals such as iron for the synthesis of organophosphorus compounds. Next, he studied cascade reactions implying catalysed reactions and electrocyclisations, to prepare complex and original structures during a project coordinated by Dr. Jean Suffert (Strasbourg University). In 2012, Fabien became lecturer at CPE Lyon and is currently conducting his research at the ICBMS.
Organofluorinated compounds represent today an important class of compounds in many fields from life sciences to materials or energy. Indeed, introduction of fluorine atoms into molecules modify their characteristics. Moreover, a modulation of different properties could be achieved thanks to the nature of the fluorinated groups introduced on a molecule. Thus, a range of various properties that can meet the needs of different fields are expected.
In that context and in order to extend the panel of available fluorinated molecules, our aim is to develop efficient synthetic methodologies for the incorporation of various fluorinated groups into organic molecules, in particular by association of fluorinated groups and heteroatoms.
Study of a Stable “Trifluoromethoxide Anion Solution” Arising from 2,4‐Dinitro‐Trifluoromethoxybenzene; Bonnefoy, C.; Chefdeville, E.; Panosian, A.; Hanquet, G.; Leroux, F. R.; Toulgoat, F.; Billard, T. Chem. Eur. J. 2021, 27, 15986–15991
Chemistry of OCF3, SCF3, and SECF3 Functional Groups; Toulgoat, F.; Liger, F.; Billard, T. In Organofluorine Chemistry; Szabó, K., Selander, N., Eds.; Wiley, 2021; pp 49–97
Asymmetric Brønsted Acid Catalyzed Isoindoline Synthesis: Enhancement of Enantiomeric Ratio by Stereoablative Kinetic Resolution; Enders, D.; Narine, A. A.; Toulgoat, F.; Bisschops, T. Angew. Chem. Int. Ed. 2008, 47, 5661–5665
An Efficient Preparation of New Sulfonyl Fluorides and Lithium Sulfonates; Toulgoat, F.; Langlois, Bernard. R.; Médebielle, M.; Sanchez, J.-Y. J. Org. Chem. 2007, 72, 9046–9052.
A. Loison, G. Hanquet, F. Toulgoat, T. Billard, A. Panossian and F. R. Leroux
Clémence Bonnefoy, Armen Panossian, Gilles Hanquet, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard
A. Loison, G. Hanquet, F. Toulgoat, T. Billard, A. Panossian, F. R. Leroux
Clémence Bonnefoy, Emmanuel Chefdeville, Christian Tourvieille, Armen Panossian, Gilles Hanquet, Frédéric Leroux, Fabien Toulgoat, Thierry Billard
Clémence Bonnefoy, Emmanuel Chefdeville, Armen Panossian, Gilles Hanquet, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard