forme_membres_ICBMS Mme Sylvie MOEBS-SANCHEZ

Mme Sylvie MOEBS-SANCHEZ

Assistant Professor INSA Lyon

sylvie.moebs@insa-lyon.fr

Bio

Sylvie Moebs-Sanchez is Assistant Professor in INSA-Lyon and in ICBMS (UMR 5246) in Villeurbanne, France. After a PhD on the synthesis of oligoarabinofuranosides from Mycobacterium cell wall in Toulouse, post-doctoral studies were conducted, in Bristol (UK) with GlaxoSmithKline and Prof. Tim Gallagher on the synthesis of bicyclic -lactams. In 2005, she joined Dr Bourissou's group in Toulouse to first tackle the synthesis of monomers, then to investigate phosphine boranes as organocatalysts. Since 2007, she has been working on multi-step synthesis from bio-based alcohols such as carbohydrates, quinic acid, isosorbide, or HMF  to prepare glycomonomers, glycolipids, organocatalysts, or new heterocyclic structures.

ORCID : 0000-0003-4197-1826

 

Research interests

I have been working on multi-step synthesis from bio-based alcohols such as carbohydrates, quinic acid, isosorbide, or HMF to prepare glycomonomers, glycolipids, organocatalysts, analogs of bioactive molecules or new heterocyclic structures while developing synthetic methodologies towards these various targets.

    « Design and synthesis of 3, 5- hetero diesters of 4-deoxy quinic acid and their aphicidal activity against Acyrthosiphon pisum », Li, X.; Sivignon, C.; da Silva, P.; Rahbé, Y.; Queneau, Y.; Moebs-Sanchez, S. *, Tetrahedron 2021, 83, 131982-131992.
    « Diastereoselective Iridium-Catalyzed Amination of Biosourced Isohexides Through Borrowing Hydrogen Methodology », Jacolot, M., Moebs-Sanchez, S., Popowycz, F. J. Org. Chem. 2018, 83, 9456-9463. Highlighted in Synfacts, 2018, 1152.
    «The Piancatelli reaction and its variants: recent applications of an underused transformation to high added-value chemicals and biomass valorization», Verrier, C., Moebs-Sanchez S., Queneau, Y. and Popowycz F. Org. Biomol. Chem. 2018, 16, 676-687. Selected as Hot article by RSC
    «Ring opening of epoxidized methyl or ethyl oleate by alkyl glycosides », Epoune Lingome, C., Gadenne, B., Alfos, C., Queneau Y. and Moebs-Sanchez S.*, Eur. J. Lipid Sci. Technol., 2017, 119, 7, 1600413.
    « New bio-based amides from renewable isosorbide through direct and atom-economical B(OH)3 methodology », Janvier, M., Moebs-Sanchez S. and Popowycz, F. Eur. J. Org. Chem., 2016, 2308-2318. Selected by Wiley-Ch as hot topics in 2016
 

Publications Find the most recent scientific contributions

Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System

Julie Carrard , Fiona Ratajczak , Joséphine Elsens , Catherine Leroy , Rebekah Kong , Lucie Geoffroy , Arnaud Comte , Guy Fournet , Benoît Joseph , Xiubin Li , Sylvie Moebs-Sanchez, Fabrice Lejeune

Biomedicines 2023, 11(10), 2801

Read the whole publication

Contact us We are open to any
new scientific partnership!

Contact us