forme_membres_ICBMS Mme Florence POPOWYCZ

Mme Florence POPOWYCZ

Professor

Florence.popowycz@insa-lyon.fr
04.81.92.99.01

Bio

Prof. Florence Popowycz got her PhD with Prof. Pierre Vogel in 2003 from the Ecole Polytechnique Fédérale de Lausanne (EPFL) after working on mannosidase inhibitors. After a 1-year post-doctoral stay in Geneva, she moved to Lyon where she holds now a full professor position at the Institut National des Sciences Appliquées (INSA). Her main interests are devoted to the development of new synthetic methodologies and its applications to heterocyclic scaffolds. Dr. Popowycz has authored more than 70 manuscripts and 6 patents.
ORCID Number: 0000-0002-0297-295X

Selected publications

1) Ruiz, J.; Oger, P.; Soulère, L.; Popowycz, F. “Straightforward synthesis of chiral terpenoid building blocks by Ru-catalyzed enantioselective hydrogenation” J. Org. Chem. 2021, 86, 9396.

2) Verrier, C.; Moebs-Sanchez, S.; Queneau, Y.; Popowycz, F.* "The Piancatelli Reaction and its Variants: Recent Applications to High Added-Value Chemicals and Biomass Valorization" Org. Biomol. Chem. 2018, 16, 676.

3) Bahé, F.; Grand, L.; Cartier, E.; Jacolot, M.; Moebs-Sanchez, S.; Portinha, D.; Fleury, E.; Popowycz, F. "Diastereoselective iridium-catalyzed amination of biosourced Isohexides through borrowing hydrogen methodology" J. Org. Chem. 2018, 9456.

4) Fan, W.; Queneau, Y.; Popowycz, F.*; "HMF in multicomponent reactions: utilization of 5-hydroxymethylfurfural (HMF) in the Biginelli reaction" Green Chem. 2018, 20, 485.

5) Lavrard, H.; Larini, P.; Popowycz, F.* "Superacidic cyclization of activated anthranilonitriles into 2-unsubstituted-4-aminoquinolines" Org. Lett. 2017, 19, 4203.

Publications Find the most recent scientific contributions

Access to Saturated Aza-Heterocycles using the Borrowing Hydrogen Methodology

Maïwenn Jacolot; Florence Popowycz

https://doi.org/10.1002/ejoc.202301119

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Ir–Na cooperativity controls the diastereoselectivity of borrowing hydrogen C–C alkylation on isosorbide: synthesis methodology and mechanistic investigation

Jordan François, Jordan Rio, Erwann Jeanneau, Marie-Ève L. Perrin, Maïwenn Jacolot, Pierre-Adrien Payard and Florence Popowycz

DOI 10.1039/D3QO00700F

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Synthesis of phospholipids under plausible prebiotic conditions and analogies with phospholipid biochemistry for origin of life studies

Michele Fiore,* Carolina Chieffo, Augustin Lopez, Dimitri Fayolle, Johal Ruiz, Laurent Soulère, Philippe Oger, Emiliano Altamura, Florence Popowycz, René Buchet

Astrobiology 2022, 22, 598–627

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