Bio
Flavien Ponsot got his PhD at the University of Burgundy, under the supervision of Pr. Claude Gros and Dr. Nicolas Desbois, in 2020. During his thesis, worked on the synthesis of new fluorophores emitting in the near infrared and the design of fluorescent probes for the detection of enzymatic activities. He then joined Pr. Stefan W. Hell at Max Planck Institute for Biophysical Chemistry for a one-year post-doctoral fellowship where he worked on the synthesis of fluorescent tags for super-resolution microscopy applications. He joined COB team at ICBMS on January 2022 for an 18-months post-doctoral fellowship. He is currently working on the synthesis of new anticoagulants under the supervision of Pr. Florence Popowycz and Dr. Maïwenn Jacolot.
Research interests
Anticoagulants, heterocyclic chemistry, fluorescence, probes, biosensing/bioimaging
Selected publications
Flavien Ponsot, Weida Shen, Pichandi Ashokkumar, Etienne Audinat, Andrey S. Klymchenko and Mayeul Collot, PEGylated red-emitting calcium probe with improved sensing properties for neuroscience, ACS Sens., 2017, 2 (11), 1706-1712.
Flavien Ponsot, Nicolas Desbois, Léo Bucher, Mathieu Berthelot, Pritam Mondal, Claude P. Gros and Anthony Romieu, Near-infrared emissive bacteriochlorin-diketopyrrolopyrrole triads: Synthesis and photophysical properties, Dyes Pigm., 2019, 160, 747-756.
Sébastien Jenni*, Flavien Ponsot*, Pierre Baroux, Lucile Collard, Takayuki Ikeno, Kenjiro Hanaoka, Valentin Quesneau, Kévin Renault, Anthony Romieu, Design, synthesis and evaluation of enzyme-responsive fluorogenic probes based on pyridine-flanked diketopyrrolopyrrole dyes, Spectrochim. Acta, Part A, 2021, 248, 119179.
Ayse Aktalay, Flavien Ponsot, Mariano L. Bossi, Vladimir N. Belov, Stefan W. Hell, Cleavable linker incorporation into a synthetic dye-nanobody-fluorescent protein assembly: FRET, FLIM and STED microscopy, ChemBioChem, 2022, 23, e2022003.