forme_membres_ICBMS Mme Fabienne FACHE

Mme Fabienne FACHE

fabienne.fache@univ-lyon1.fr

Bio

Fabienne obtained her undergraduate degree from the University of Lyon (ESCIL now CPE Lyon & UCBL) and completed her MSc’s research under the supervision of Dr Jean-Marie Basset (CNRS, Lyon), working in the field of organometallic chemistry. She then moved to Strasbourg to pursue doctoral studies under the supervision of Dr Pierre Albrecht (CNRS, Université Louis Pasteur), working on Organic Geochemistry. After obtaining her PhD degree in 1990, she joined the group of Dr Pierre Gallezot (IRCELyon) as a postdoctoral fellow, where she worked on the oxidation of glyoxal into glyoxylic acid by heterogeneous catalysis in collaboration with the company Hoechst France. In 1991, she was appointed CNRS researcher. In 1999, she received the bronze medal of CNRS.

Since 2000, she belongs to the group of Prof. Olivier Piva (UCBL).

Outside of the lab, Fabienne enjoys playing guitar, reading, cooking and playing sports.

Research interests

Since she entered the CNRS Fabienne has dedicated a large part of her researches to Atom Economy. Therefore, she developed heterogeneous catalytic methods for organic chemistry, asymmetric catalytic systems, tandem reactions, and methodologies in non-conventional media (ionic liquids, new solvents …) and applied them in total synthesis. Recently, she started working with atmospheric chemists, to try to understand the mechanism of degradation of terpenes released by plants.

Selected publications

“Green chemistry: solvent- and metal-free Prins cyclization. Application to sequential reactions”, D. Clarisse, B. Pelotier, O. Piva and F. Fache*, Chem. Commun., 48, 157 (2012).

“First example of the use of biosourced alkyl levulinates as solvent for synthetic chemistry : application to the heterogeneously catalyzed Heck coupling” R. Marcel, T. Durillon, L. Djakovitch, F. Fache,* F. Rataboul*,ChemistrySelect, 4, 3329-3333 (2019).

“Reactions of organic peroxy radicals, RO2, with substituted and biogenic alkenes at room temperature: unsuspected sinks for some RO2 in the atmosphere” B. Noziere*, F. Fache. Chem. Sci., 12, 11676-83 (2021).

Publications Find the most recent scientific contributions

The reaction of organic peroxy radicals with unsaturated compounds controlled by a non-epoxide pathway under atmospheric conditions

B. Nozière, O. Durif, E. Dubus, S. Kylington, A. Emmer, F. Fache, F. Piel, A. Wisthaler

Phys. Chem. Chem. Phys., 2023, 25, 7772

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Access to hexahydroindeno[2,1-c]pyran based propellanes by a domino Prins/friedel-Crafts cyclization

Youssef Nassar, Fabienne Fache, Béatrice Pelotier, Olivier Piva

Synthesis, 2022, 54, 4622-4628.

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Reactions of organic peroxy radicals, RO2, with substituted and biogenic alkenes at room temperature: unsuspected sinks for some RO2 in the atmosphere

Barbara Nozière, Fabienne Fache

Chem. Sci. 2021, 12, 11676-11683.

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Caryatin and 3’-O-methylcaryatin contents in edible yams (Dioscorea spp.)

Benjamin Fel, Anne Baudouin, Fabienne Fache, Sonia Czarnes, Vincent Lebot, Laurent Legendre

Journal of Food Composition and Analysis 2021, 102, 104010.

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First Example of the Use of Biosourced Alkyl Levulinates as Solvents for Synthetic Chemistry: Application to the Heterogeneously Catalyzed Heck Coupling

Romane Marcel, Thibault Durillon, Laurent Djakovitch, Fabienne Fache, Franck Rataboul

ChemistrySelect, 2019, 4, 3329– 3333

Read the whole publication

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