Research areaBiochemistry and Molecular Biology

The main research themes of the Biochemistry and Molecular Biology cluster of the ICBMS extend to the understanding of molecular mechanisms and the mechanisms of interactions between biomolecules and cellular components, in particular:

• Regulation of enzyme expression and activity and their link to the metabolic syndrome, with emphasis on alkaline phosphatase, phospholipase D and sphingosine kinase in the process of tissue calcification and ossification.
• Characterization of the structure-interactions-functions of extracellular matrix with a focus on intrinsically disordered extracellular proteins and proteoglycans, and on glycosaminoglycans.
• The understanding and use of the mechanisms of interactions between biomolecules or cellular components with electrochemical, optical and/or 3D materials while keeping the understanding of biochemical phenomena as a framework.