Chemistry at the interface with Biology and MedicineSysChem: Complex prebiotic and biomolecular systems
SysChem stands for "systems chemistry of biomolecules and prebiotic chemistry". We are generally studying the systemic interactions between synthetic lipophilic peptides, synthetic nucleic acids and racemic, scalemic or natural phospholipids to approach the self-evolution of synthetic living cells. The growth and division of giant phospholipid vesicles is one major research topic. We are studying the mechanism and scope of the phosphorylation of alkanols, nucleosides and glycerols under prebiotic conditions. We also engage in developing synthetic vaccines based on glycolipid vesicles.
More about the SysChem group members and recent publications at: https://www.icbms.fr/en/team/20-lco2-html
Publications Find the most recent scientific contributions
The Use of 5-Hydroxymethylfurfural (5-HMF) in Multi- Component Hantzsch Dihydropyridine Synthesis
Jingjing Jiang, Yves Queneau, Florence Popowycz
ChemSusChem 2024, e202301782
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3D MODEL of an anatomically inert human hand: feasibility study
Lucchino, N.; Pialat, J-B.; Marquette, C.; Courtial, E.; Erhard, L.; Voulliaume, D.; Mojallal, A.; Gazarian, A.
Hand Surgery and Rehabilitation 101709
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Hydride-free reduction of propargyl electrophiles: A nickel-catalyzed photoredox strategy for allene synthesis
Hu, Tingjun; Fagué, Vincent; Bouyssi, Didier; Monteiro, Nuno; Amgoune, Abderrahmane
Green Chem, 2024, Accepted Manuscript
Read the whole publicationStereodivergent, kinetically controlled isomerization of terminal alkenes via nickel catalysis.
Rubel, Camille Z.; Ravn, Anne K.; Ho, Hang Chi; Yang, Shenghua; Li, Zi-Qi; Engle, Keary Mark; Vantourout, Julien C.
Angew. Chem. Int. Ed. 2024, e202320081
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Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties
Clémence Bonnefoy, Adrien Gallego, Clément Delobel, Betty Raynal, Maxime Decourt, Emmanuel Chefdeville, Gilles Hanquet, Armen Panossian, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard