Publications
Structural determination and kinetic analysis of the Transketolase from Vibrio vulnificus reveal unexpected cooperative behavior.
Georges, R.-N., Ballut, L., Octobre, B., Comte, A., Hecquet, L., Charmantray, F.*, Doumèche, B.
Protein Science, 2024, 33(3):e4884
Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System
Julie Carrard , Fiona Ratajczak , Joséphine Elsens , Catherine Leroy , Rebekah Kong , Lucie Geoffroy , Arnaud Comte , Guy Fournet , Benoît Joseph , Xiubin Li , Sylvie Moebs-Sanchez, Fabrice Lejeune
Biomedicines 2023, 11(10), 2801
Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25
Riheb Jabeur, Caroline Corbel, Pascal Loyer, Annabelle Le Parc, Adélaide Le Grand, Arnaud Comte, Stéphane Bach, Gwenaëlle André-Leroux, Olivier Sire, Hedi Ben Mansour, and Véronique Le Tilly
Biochemistry, 2023
An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation
A. Caputo, S. Sartini, E. Levati, I. Minato, G. M. Elisi, A. Di Stasi, C. Guillou, P. G. Goekjian, P. Garcia, D. Gueyrard, S. Bach, A. Comte, S. Ottonello, S. Rivara, B. Montanini*
Antibiotics 2022, 11, 1449
Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death
Claire Delehouzé, Arnaud Comte, Marcelle Hauteville, Peter Goekjian, Marie-Thérèse Dimanche-Boitrel, Morgane Rousselot, and Stéphane Bach
Scientific Reports 2022, 12, 5118
Phospholipase D inhibitors screening: Probing and evaluation of ancient and novel molecules
Arhab, Y; Bessaa, K; Abla, H.; Aydin, M.; Comte, A.; Brizuela, L.; Mebarek, S.; Perret, F.; Cherrier, M.; Abousalham, A.; Noiriel, A.
Colloids Surf. A Physicochem. Eng. Asp. 2021, 630, 127629
Racemic Phospholipids for Origin of Life Studies
Emiliano Altamura, Arnaud Comte, Alice D’Onofrio, Charlotte Roussillon, Dimitri Fayolle, René Buchet, Fabio Mavelli, Pasquale Stano, Michele Fiore,* Peter Strazewski*
Symmetry 2020, 12, 1108
Innovative Electrochemical Screening Allows Transketolase Inhibitors to Be Identified
Aymard, C. M. G.; Halma, M.; Comte, A.; Mousty, C.; Prévot, V.; Hecquet, L.; Charmantray, F.; Blum, L. J.; Doumèche, B.
Anal. Chem. 2018, 90, 15, 9241–9248
Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes
Garcia-Lopez, A.; Tessaro, F.; Jonker, Hendrik R. A.; Wacker, A.; Richter, C.; Comte, A.; Berntenis, N.; Schmucki, R.; Hatje, K.; Petermann, O.; Chiriano, G.; Perozzo, R; Sciarra, D.; Konieczny, K.; Faustino, I.; Fournet, G.; Orozco, M.; Metzger, F.; Ebeling, M.; Goekjian, P.; Joseph, B.; Schwalbe, H.; Scapozza, L.