An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation

A. Caputo, S. Sartini, E. Levati, I. Minato, G. M. Elisi, A. Di Stasi, C. Guillou, P. G. Goekjian, P. Garcia, D. Gueyrard, S. Bach, A. Comte, S. Ottonello, S. Rivara, B. Montanini*

Antibiotics 2022, 11, 1449

Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death

Claire Delehouzé, Arnaud Comte, Marcelle Hauteville, Peter Goekjian, Marie-Thérèse Dimanche-Boitrel, Morgane Rousselot, and Stéphane Bach

Scientific Reports 2022, 12, 5118

Phospholipase D inhibitors screening: Probing and evaluation of ancient and novel molecules

Arhab, Y; Bessaa, K; Abla, H.; Aydin, M.; Comte, A.; Brizuela, L.; Mebarek, S.; Perret, F.; Cherrier, M.; Abousalham, A.; Noiriel, A.

Colloids Surf. A Physicochem. Eng. Asp. 2021, 630, 127629

Racemic Phospholipids for Origin of Life Studies

Emiliano Altamura, Arnaud Comte, Alice D’Onofrio, Charlotte Roussillon, Dimitri Fayolle, René Buchet, Fabio Mavelli, Pasquale Stano, Michele Fiore,* Peter Strazewski*

Symmetry 2020, 12, 1108

Innovative Electrochemical Screening Allows Transketolase Inhibitors to Be Identified

Aymard, C. M. G.; Halma, M.; Comte, A.; Mousty, C.; Prévot, V.; Hecquet, L.; Charmantray, F.; Blum, L. J.; Doumèche, B.

Anal. Chem. 2018, 90, 15, 9241–9248

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

Garcia-Lopez, A.; Tessaro, F.; Jonker, Hendrik R. A.; Wacker, A.; Richter, C.; Comte, A.; Berntenis, N.; Schmucki, R.; Hatje, K.; Petermann, O.; Chiriano, G.; Perozzo, R; Sciarra, D.; Konieczny, K.; Faustino, I.; Fournet, G.; Orozco, M.; Metzger, F.; Ebeling, M.; Goekjian, P.; Joseph, B.; Schwalbe, H.; Scapozza, L.

Nature Communications, 2019, 9(1), 1-12

6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury

Delehouze, C.; Leverrier-Penna, S.; Le Cann, F.; Comte, A.; Jacquard-Fevai, M.; Delalande, O.; Desban, N.; Baratte, B.; Gallais, I.; Faurez, F.; Bonnet, M.; Hauteville, M.; Goekjian, P.; Thuillier, R.; Favreau, F.; Vandenabeele, P.; Bach S.; Dimanche-Boitrel M. T.

Scientific Reports volume 7, Article number: 12931 (2017)

Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis

Le Cann, F.; Delehouze, C.; Leverrier-Penna, S.; Filliol, A.; Comte, A.; Delalande, O.; Desban, N.; Baratte, B.; Gallais, I.; Piquet-Pellorce, C.; Faurez, F.; Bonnet, M.; Mettey, Y.; Goekjian, P.; Samson, M.; Vandenabeele, P.; Bach S.; Dimanche-Boitrel M. T.

FEBS J. 2017, 18, 3050-3068

Synthesis of 1-Indanols and 1-Indanamines by Intramolecular Palladium(0)-Catalyzed C(sp3)H Arylation: Impact of Conformational Effects

Janody, S.; Jazzar, R.; Comte, A.; Holstein, P. M.; Vors, J-P.; Ford, M. J.; Baudoin, O.

Chem. Eur. J. 2014, 20, 11084-11090

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