Publications
An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation
A. Caputo, S. Sartini, E. Levati, I. Minato, G. M. Elisi, A. Di Stasi, C. Guillou, P. G. Goekjian, P. Garcia, D. Gueyrard, S. Bach, A. Comte, S. Ottonello, S. Rivara, B. Montanini*
Antibiotics 2022, 11, 1449
Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death
Claire Delehouzé, Arnaud Comte, Marcelle Hauteville, Peter Goekjian, Marie-Thérèse Dimanche-Boitrel, Morgane Rousselot, and Stéphane Bach
Scientific Reports 2022, 12, 5118
Phospholipase D inhibitors screening: Probing and evaluation of ancient and novel molecules
Arhab, Y; Bessaa, K; Abla, H.; Aydin, M.; Comte, A.; Brizuela, L.; Mebarek, S.; Perret, F.; Cherrier, M.; Abousalham, A.; Noiriel, A.
Colloids Surf. A Physicochem. Eng. Asp. 2021, 630, 127629
Racemic Phospholipids for Origin of Life Studies
Emiliano Altamura, Arnaud Comte, Alice D’Onofrio, Charlotte Roussillon, Dimitri Fayolle, René Buchet, Fabio Mavelli, Pasquale Stano, Michele Fiore,* Peter Strazewski*
Symmetry 2020, 12, 1108
Innovative Electrochemical Screening Allows Transketolase Inhibitors to Be Identified
Aymard, C. M. G.; Halma, M.; Comte, A.; Mousty, C.; Prévot, V.; Hecquet, L.; Charmantray, F.; Blum, L. J.; Doumèche, B.
Anal. Chem. 2018, 90, 15, 9241–9248
Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes
Garcia-Lopez, A.; Tessaro, F.; Jonker, Hendrik R. A.; Wacker, A.; Richter, C.; Comte, A.; Berntenis, N.; Schmucki, R.; Hatje, K.; Petermann, O.; Chiriano, G.; Perozzo, R; Sciarra, D.; Konieczny, K.; Faustino, I.; Fournet, G.; Orozco, M.; Metzger, F.; Ebeling, M.; Goekjian, P.; Joseph, B.; Schwalbe, H.; Scapozza, L.
Nature Communications, 2019, 9(1), 1-12
6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury
Delehouze, C.; Leverrier-Penna, S.; Le Cann, F.; Comte, A.; Jacquard-Fevai, M.; Delalande, O.; Desban, N.; Baratte, B.; Gallais, I.; Faurez, F.; Bonnet, M.; Hauteville, M.; Goekjian, P.; Thuillier, R.; Favreau, F.; Vandenabeele, P.; Bach S.; Dimanche-Boitrel M. T.
Scientific Reports volume 7, Article number: 12931 (2017)
Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis
Le Cann, F.; Delehouze, C.; Leverrier-Penna, S.; Filliol, A.; Comte, A.; Delalande, O.; Desban, N.; Baratte, B.; Gallais, I.; Piquet-Pellorce, C.; Faurez, F.; Bonnet, M.; Mettey, Y.; Goekjian, P.; Samson, M.; Vandenabeele, P.; Bach S.; Dimanche-Boitrel M. T.
FEBS J. 2017, 18, 3050-3068
Synthesis of 1-Indanols and 1-Indanamines by Intramolecular Palladium(0)-Catalyzed C(sp3)H Arylation: Impact of Conformational Effects
Janody, S.; Jazzar, R.; Comte, A.; Holstein, P. M.; Vors, J-P.; Ford, M. J.; Baudoin, O.