forme_membres_ICBMS Prof Olivier PIVA

Prof Olivier PIVA

Professor and Head of ICBMS

olivier.piva@univ-lyon1.fr
04.72.44.81.36

Bio

Olivier Piva studied chemistry at the University of Reims and obtained his Ph-D with Prof. J.P. Pete (1988). Following a postdoctoral stay with Prof. D. Enders (RWTH), he joined in 1989 the CNRS as Chargé de recherche. He was a NATO research associate with Prof. S.V. Ley (Cambridge Univ.) in 1995. He was promoted full Professor at Univ. Lyon 1 in 1998. His research interests encompass photochemistry, metathesis, tandem reactions and their applications to natural product synthesis.

Orcid

Research interests

Initially centered on the study of asymmetric photochemical reactions, our research has shifted towards atom- and step economy processes involving metathesis (in tandem and sequential mode) or the formation of heterocycles (lactones and THP using the Prins reaction). These different processes were successfully applied to the synthesis of natural products. More recenttly, we have also investigated new accesses to propellanes and spiranic compounds.

Selected publications

- Merging metathesis and photochemical Csp3-H activation: Access to masked b-formyl hexanolides and their rearrangement to furofuranones. Glenadel, Q.; Nassar, Y.; Raffier, L.; Veys, S.; Piva, O. Tetrahedron 2018, 74, 5367-5373.

- Formal enantioselective synthesis of nhatrangin A. Feuillastre, S.; Rafier, L.; Pelotier, B.; Piva, O. Org. Biomol. Chem. 2020, 18, 1949-1956.

- A Short route to access oxaspiro[n,3,3]propellanes. Nassar, Y; Piva, O. Org. Biomol. Chem. 2020, 18, 5811-5815.

Textbook: Retrosynthetic Analysis and Synthesis of Natural Products - O. Piva - Wiley 2019 - ISBN 9-781786-303493.

Publications Find the most recent scientific contributions

Organozinc reagents and nickel

O. Piva

Organozinc Derivatives and Transition Metal Catalysts: Formation of C-C Bonds by Cross-coupling, Ed. J. Cossy, De Gruyter 2023, pp. 63-116

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Access to hexahydroindeno[2,1-c]pyran based propellanes by a domino Prins/friedel-Crafts cyclization

Youssef Nassar, Fabienne Fache, Béatrice Pelotier, Olivier Piva

Synthesis, 2022, 54, 4622-4628.

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Five-Membered Rings With Three Oxygen or Sulfur Atoms in 1,2,3-Positions

Olivier Piva

Comprehensive Heterocyclic Chemistry IV, 2022, Vol. 6, pp 120-145.

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Photoredox-catalyzed hydroxymethylation of β-ketoesters: application to the synthesis of [3.3.3] propellane lactones

Youssef Nassar, Olivier Piva*

Org. Biomol. Chem. 2021, 19, 9251-9259.

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Design, Synthesis, and Evaluation of α-(Hydroxymethyl)cycloalkanols

Youssef Nassar, Olivier Piva

Eur. J. Org. Chem. 2021, 1037-1054.

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