Research areaBiochemistry and Molecular Biology
The main research themes of the Biochemistry and Molecular Biology cluster of the ICBMS extend to the understanding of molecular mechanisms and the mechanisms of interactions between biomolecules and cellular components, in particular:
- Regulation of enzyme expression and activity and their link to the metabolic syndrome, with emphasis on alkaline phosphatase, phospholipase D and sphingosine kinase in the process of tissue calcification and ossification.
- Characterization of the structure-interactions-functions of extracellular matrix with a focus on intrinsically disordered extracellular proteins and proteoglycans, and on glycosaminoglycans.
- The understanding and use of the mechanisms of interactions between biomolecules or cellular components with electrochemical, optical and/or 3D materials while keeping the understanding of biochemical phenomena as a framework.
Research topics ICBMS expertises
Publications Find the most recent scientific contributions
How can we solve the problem of bioprintability to overcome the bioprinting challenges?
Alizée Mosnier, Imen Halima & Edwin-Joffrey Courtial
MRS Bulletin (2024)
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Unlocking the potential of bio-inspired bioinks: A collective breakthrough in mammalian tissue bioprinting
Marquette, C. A.; Chastagnier, L.; Da Sousa, B.; Chocarro-Wrona, C.; Courtial, E.-J.; Rae, E.; Thomann, C.; Carre, A.; Essayan, L.; Pasuch, A. J.; Mosnier, A.; Devillard, C.; Petiot, E.; Lemarié, L.; Matera, E.-L.; Simoes, M.; Dumontet, C.; Cuella Martin, C.; Pechtimaldjian, L.; Pécheur, E.-I.; Maguer-Satta, V.; Michelet, M.; Plissonnier, M.-L.; Archer, F.; Moreau, K.; Dufaud, M.; Zaupa, C.; Balloul, J.-M.; Pruvost, Q.; Dauphin, T.; Mosser, M.; Pragnère, S.,
Bioprinting, 2024, 41: e00351
Read the whole publicationSpace radiation damage rescued by inhibition of key spaceflight associated miRNAs
J. Tyson McDonald, Jang Keun Kim,Lily Farmerie,Meghan L. Johnson, Nidia S. Trovao, Shehbeel Arif, Keith Siew, Sergey Tsoy, Yaron Bram, Jiwoon Park,EliahOverbey,Krista Ryon, Jeffrey Haltom, Urminder Singh, Francisco J. Enguita, Victoria Zaksas, Joseph W. Guarnieri, Michael Topper, Douglas C. Wallace, Cem Meydan, Stephen Baylin, Robert Meller, Masafumi Muratani, D.Marshall Porterfield, Brett Kaufman, Marcelo A. Mori, Stephen B. Walsh, Dominique Sigaudo-Roussel, Saida Mebarek, Massimo Bottini, Christophe A. Marquette, Eve Syrkin Wurtele, Robert E. Schwartz, DiegoGaleano, Christopher E. Mason, Peter Grabham & Afshin Beheshti
Nat. Commun. 2024, 15: 4825
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Convergent synthesis of N-(4-(3-ethoxy-2-hydroxypropyl)phenyl)-2-(methylthio) acetamide precursor of the suplatast tosylate
Margherita Colombo, Yousef Joqmara, Guillaume Pilet, Michele Fiore
Trends in Organic Chemistry, 2024, 24, 79-92
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