Biochemistry and Molecular BiologyMechanisms and understanding of biomolecules and cellular components’ interactions with electrochemical, optical and 3D polymeric materials.

The team "Génie Enzymatique, Membranes Biomimétiques et Assemblages Supramoléculaires" develops interdisciplinary research activities in the fields of biocatalysis and specific biomolecular recognition at the interface of biochemistry, chemistry, physico-chemistry and biology. The focus is the study of enzymes and biomolecules in structured media for the design of biosensors, biochips, lab-on-a chips, bioelectronics interfaces and biomimetic membranes. These activities have led us to develop original methods and techniques for the functionalization of various types of synthetic supports and for the immobilization of biomolecules. In this field, a recent orientation concerns 3D bioprinting.

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Publications Find the most recent scientific contributions

Hydride-free reduction of propargyl electrophiles: A nickel-catalyzed photoredox strategy for allene synthesis

Hu, Tingjun; Fagué, Vincent; Bouyssi, Didier; Monteiro, Nuno; Amgoune, Abderrahmane

Green Chem, 2024, Accepted Manuscript

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Stereodivergent, kinetically controlled isomerization of terminal alkenes via nickel catalysis.

Rubel, Camille Z.; Ravn,  Anne K.; Ho, Hang Chi; Yang, Shenghua; Li, Zi-Qi; Engle, Keary Mark; Vantourout, Julien C.

Angew. Chem. Int. Ed. 2024, e202320081

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Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties

Clémence Bonnefoy, Adrien Gallego, Clément Delobel, Betty Raynal, Maxime Decourt, Emmanuel Chefdeville, Gilles Hanquet, Armen Panossian, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard

Eur. J. Org. Chem. 2024, 27, e202400142

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Machine learning approaches for the identification of ligands of the autophagy marker LC3

Laurent Soulère, Yves Queneau

Artificial Intelligence Chemistry 1(2) (2023) 100022

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Importance of the 2,6-Difluorobenzamide Motif for FtsZ Allosteric Inhibition: Insights from Conformational Analysis, Molecular Docking and Structural Modifications

T. Barbier, O. Dumitrescu, G. Lina, Y. Queneau, L. Soulère

Molecules, 2023, 28(5), 2055

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