Biochemistry and Molecular BiologyMechanisms and understanding of biomolecules and cellular components’ interactions with electrochemical, optical and 3D polymeric materials.
The team "Génie Enzymatique, Membranes Biomimétiques et Assemblages Supramoléculaires" develops interdisciplinary research activities in the fields of biocatalysis and specific biomolecular recognition at the interface of biochemistry, chemistry, physico-chemistry and biology. The focus is the study of enzymes and biomolecules in structured media for the design of biosensors, biochips, lab-on-a chips, bioelectronics interfaces and biomimetic membranes. These activities have led us to develop original methods and techniques for the functionalization of various types of synthetic supports and for the immobilization of biomolecules. In this field, a recent orientation concerns 3D bioprinting.
Publications Find the most recent scientific contributions
Paper-based electrodes as a tool for detecting ligninolytic enzymatic activities
Fall, I., Doumèche, B., Abdellaoui, S., Rémond C., Rakotoarivonina, H., Ochs M.
Bioelectrochem. 2023, 156, 108609
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Synthetic outer membrane vesicles bearing Tn antigen
Carolina Chieffo, Arnaud Comte, Peter Strazewski and Michele Fiore*
European Journal of Organic Chemistry 2023
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Difluoromethoxylated Ketones as Building Blocks for the Synthesis of Challenging OCF2H-Bearing N-Heterocycles
A. Loison, G. Hanquet, F. Toulgoat, T. Billard, A. Panossian and F. R. Leroux
Eur. J. Org. Chem. 2023, 26, e202300695
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The origin and early evolution of life: homochirality emergence in prebiotic environments
Carolina Chieffo, Anastasiia Shvetsova, Fryni Skorda, Augustin Lopez, and Michele Fiore*
Astrobiology 2023, 23
Read the whole publicationIdentifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System
Julie Carrard , Fiona Ratajczak , Joséphine Elsens , Catherine Leroy , Rebekah Kong , Lucie Geoffroy , Arnaud Comte , Guy Fournet , Benoît Joseph , Xiubin Li , Sylvie Moebs-Sanchez, Fabrice Lejeune