Biochemistry and Molecular BiologyMechanisms and understanding of biomolecules and cellular components’ interactions with electrochemical, optical and 3D polymeric materials.

The team "Génie Enzymatique, Membranes Biomimétiques et Assemblages Supramoléculaires" develops interdisciplinary research activities in the fields of biocatalysis and specific biomolecular recognition at the interface of biochemistry, chemistry, physico-chemistry and biology. The focus is the study of enzymes and biomolecules in structured media for the design of biosensors, biochips, lab-on-a chips, bioelectronics interfaces and biomimetic membranes. These activities have led us to develop original methods and techniques for the functionalization of various types of synthetic supports and for the immobilization of biomolecules. In this field, a recent orientation concerns 3D bioprinting.

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Publications Find the most recent scientific contributions

How can we solve the problem of bioprintability to overcome the bioprinting challenges?

Alizée Mosnier, Imen Halima & Edwin-Joffrey Courtial

MRS Bulletin (2024)

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Unlocking the potential of bio-inspired bioinks: A collective breakthrough in mammalian tissue bioprinting

Marquette, C. A.; Chastagnier, L.; Da Sousa, B.; Chocarro-Wrona, C.; Courtial, E.-J.; Rae, E.; Thomann, C.; Carre, A.; Essayan, L.; Pasuch, A. J.; Mosnier, A.; Devillard, C.; Petiot, E.; Lemarié, L.; Matera, E.-L.; Simoes, M.; Dumontet, C.; Cuella Martin, C.; Pechtimaldjian, L.; Pécheur, E.-I.; Maguer-Satta, V.; Michelet, M.; Plissonnier, M.-L.; Archer, F.; Moreau, K.; Dufaud, M.; Zaupa, C.; Balloul, J.-M.; Pruvost, Q.; Dauphin, T.; Mosser, M.; Pragnère, S.,

Bioprinting, 2024, 41: e00351

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Space radiation damage rescued by inhibition of key spaceflight associated miRNAs

J. Tyson McDonald, Jang Keun Kim,Lily Farmerie,Meghan L. Johnson, Nidia S. Trovao, Shehbeel Arif, Keith Siew, Sergey Tsoy, Yaron Bram, Jiwoon Park,EliahOverbey,Krista Ryon, Jeffrey Haltom, Urminder Singh, Francisco J. Enguita, Victoria Zaksas, Joseph W. Guarnieri, Michael Topper, Douglas C. Wallace, Cem Meydan, Stephen Baylin, Robert Meller, Masafumi Muratani, D.Marshall Porterfield, Brett Kaufman, Marcelo A. Mori, Stephen B. Walsh, Dominique Sigaudo-Roussel, Saida Mebarek, Massimo Bottini, Christophe A. Marquette, Eve Syrkin Wurtele, Robert E. Schwartz, DiegoGaleano, Christopher E. Mason, Peter Grabham & Afshin Beheshti

Nat. Commun. 2024, 15: 4825

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Convergent synthesis of N-(4-(3-ethoxy-2-hydroxypropyl)phenyl)-2-(methylthio) acetamide precursor of the suplatast tosylate

Margherita Colombo, Yousef Joqmara, Guillaume Pilet, Michele Fiore

Trends in Organic Chemistry, 2024, 24, 79-92

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Biochemical, Bioinformatic, and Structural Comparisons of Transketolases and Position of Human Transketolase in the Enzyme Evolution

Biochemistry, 2024

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