SCORE

Synthesis and Catalysis in Organic, Organometallic and REdox chemistries

Welcome to the SCORE-Lab. The SCORE-Lab gathers several researchers with complementary skills and expertises to develop chemistry projects at the forefront of redox catalysis and organic synthesis. This collaborative scheme undoubtedly constitutes the greatest strength of our team and is the corner-stone of our scientific programs. Our research interests encompass synthetic organic and organometallic chemistry, transition metal catalysis, organocatalysis, photoredox catalysis, and electrochemistry. More specifically, research in the SCORE-Lab seeks to merge the rational design of molecular catalysts (organic and organometallic) with the creative use of photochemical and electrochemical techniques to efficiently and sustainably convert readily available feedstock chemicals to high added value organic scaffolds. A significant part of our efforts is dedicated to fundamental mechanistic studies of new catalytic processes through multidisciplinary approaches.

forme_membres_ICBMS Abderrahmane Amgoune

Abderrahmane Amgoune

Professor

forme_membres_ICBMS Viktor Boshevski

Viktor Boshevski

PhD student

forme_membres_ICBMS Didier Bouyssi

Didier Bouyssi

Associate Professor

forme_membres_ICBMS Coralie Duchemin

Coralie Duchemin

Postdoctoral Fellow

forme_membres_ICBMS Romain Godelier

Romain Godelier

PhD student

forme_membres_ICBMS Tingjun Hu

Tingjun Hu

PhD Student

forme_membres_ICBMS Mohammad Jaber

Mohammad Jaber

PhD student

forme_membres_ICBMS Maurice Médebielle

Maurice Médebielle

CNRS Research Director

forme_membres_ICBMS Jérémy Merad

Jérémy Merad

Associate Professor

forme_membres_ICBMS Nuno Monteiro

Nuno Monteiro

CNRS Research associate

forme_membres_ICBMS Yasemin Ozbay

Yasemin Ozbay

PhD student

forme_membres_ICBMS Kunlong Song

Kunlong Song

PhD Student

forme_membres_ICBMS Gaël Tran

Gaël Tran

CNRS research associate

forme_membres_ICBMS Julien Vantourout

Julien Vantourout

CNRS research associate

Electrochemistry is a valuable tool when it comes to midly, efficently and selectively manipulating electrons. Our group uses electrochemistry as a robust platform to quickly and efficiently develop and optimize redox processes.

forme_membres_ICBMS Abderrahmane Amgoune

Abderrahmane Amgoune

Professor

forme_membres_ICBMS Coralie Duchemin

Coralie Duchemin

Postdoctoral Fellow

forme_membres_ICBMS Maurice Médebielle

Maurice Médebielle

CNRS Research Director

forme_membres_ICBMS Jérémy Merad

Jérémy Merad

Associate Professor

forme_membres_ICBMS Nuno Monteiro

Nuno Monteiro

CNRS Research associate

forme_membres_ICBMS Julien Vantourout

Julien Vantourout

CNRS research associate

Photoredox catalysis, and photochemistry in general, is a powerful synthetic tool that leverage the ability of certain chemicals to absorb specific wavelenghts, in order to convert light energy into chemical energy. This inherently selective energy delivery allows the design of transformations that would be impossible using classical thermal activation. Our group exploits typically photoredox catalysis to generate free radicals and to couple them using other modes of catalysis (e.g. transition metal catalysis, organocatalysis, electrocatalysis).
forme_membres_ICBMS Abderrahmane Amgoune

Abderrahmane Amgoune

Professor

forme_membres_ICBMS Viktor Boshevski

Viktor Boshevski

PhD student

forme_membres_ICBMS Didier Bouyssi

Didier Bouyssi

Associate Professor

forme_membres_ICBMS Coralie Duchemin

Coralie Duchemin

Postdoctoral Fellow

forme_membres_ICBMS Romain Godelier

Romain Godelier

PhD student

forme_membres_ICBMS Tingjun Hu

Tingjun Hu

PhD Student

forme_membres_ICBMS Mohammad Jaber

Mohammad Jaber

PhD student

forme_membres_ICBMS Maurice Médebielle

Maurice Médebielle

CNRS Research Director

forme_membres_ICBMS Jérémy Merad

Jérémy Merad

Associate Professor

forme_membres_ICBMS Nuno Monteiro

Nuno Monteiro

CNRS Research associate

forme_membres_ICBMS Yasemin Ozbay

Yasemin Ozbay

PhD student

forme_membres_ICBMS Kunlong Song

Kunlong Song

PhD Student

forme_membres_ICBMS Gaël Tran

Gaël Tran

CNRS research associate

Our group investigates transition metal organometallic chemistry, with a particular interest in first row elements (Ni, Mn, Cu). We are exploring new catalytic strategies for the atom-economic coupling of C-O, C-N or C-C based electrophiles with a large scope of nucleophiles (including very mild nucleophilic partners C-H bond activation) as well as possible further functionalization reactions. We are particularly investigating new cooperative strategies that rely on the combination of purposely designed first row transition metal based catalysts with other partners (e.g. electrophilic activators, photocatalysts, electrodes). Apart from these catalytic aspects , we also have a strong expertise in the stoichiometric approach to organometallic chemistry. We are leveraging this expertise toward in-depth mechanistic studies of the reactions we design.
forme_membres_ICBMS Abderrahmane Amgoune

Abderrahmane Amgoune

Professor

forme_membres_ICBMS Viktor Boshevski

Viktor Boshevski

PhD student

forme_membres_ICBMS Didier Bouyssi

Didier Bouyssi

Associate Professor

forme_membres_ICBMS Coralie Duchemin

Coralie Duchemin

Postdoctoral Fellow

forme_membres_ICBMS Romain Godelier

Romain Godelier

PhD student

forme_membres_ICBMS Tingjun Hu

Tingjun Hu

PhD Student

forme_membres_ICBMS Mohammad Jaber

Mohammad Jaber

PhD student

forme_membres_ICBMS Maurice Médebielle

Maurice Médebielle

CNRS Research Director

forme_membres_ICBMS Jérémy Merad

Jérémy Merad

Associate Professor

forme_membres_ICBMS Nuno Monteiro

Nuno Monteiro

CNRS Research associate

forme_membres_ICBMS Yasemin Ozbay

Yasemin Ozbay

PhD student

forme_membres_ICBMS Gaël Tran

Gaël Tran

CNRS research associate

forme_membres_ICBMS Julien Vantourout

Julien Vantourout

CNRS research associate

Our group is interested in the design of original multicatalytic systems merging (enantioselective) organocatalysis with various activation modes (photocatalysis, electrochemistry) in order to setup innovative and highly controled transformations. 
forme_membres_ICBMS Maurice Médebielle

Maurice Médebielle

CNRS Research Director

forme_membres_ICBMS Jérémy Merad

Jérémy Merad

Associate Professor

forme_membres_ICBMS Kunlong Song

Kunlong Song

PhD Student

Publications Find the most recent scientific contributions

Hydride-free reduction of propargyl electrophiles: A nickel-catalyzed photoredox strategy for allene synthesis

Hu, Tingjun; Fagué, Vincent; Bouyssi, Didier; Monteiro, Nuno; Amgoune, Abderrahmane

Green Chem, 2024, Accepted Manuscript

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Stereodivergent, kinetically controlled isomerization of terminal alkenes via nickel catalysis.

Rubel, Camille Z.; Ravn,  Anne K.; Ho, Hang Chi; Yang, Shenghua; Li, Zi-Qi; Engle, Keary Mark; Vantourout, Julien C.

Angew. Chem. Int. Ed. 2024, e202320081

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Photoredox-Catalyzed α−C−H Monoalkylation of Symmetric Polyols in the Presence of CO2

Archer, Gaétan; Meyrelles, Ricardo; Eder, Isabel; Kovács, Nóra; Maryasin, Boris; Médebielle, Maurice; Merad, Jérémy

Angew. Chem. Int. Ed. 2024, e202315329

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Electroreductive Synthesis of Nickel(0) complexes

Rubel, Camille Z.; Cao, Yilin; Ewing, Tamara El-Hayek; Laudadio, Gabriele; Beutner, Gregory L.; Wisniewski, Steven R.; Wu, Xiangyu; Baran, Phil S.; Vantourout, Julien C.; Engle, Keary M.

Angew. Chem. Int. Ed. 2023, 136, 2, e202311557

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Electrochemically Driven Nickel-Catalyzed Halogenation of Unsaturated Halide and Triflate Derivatives

Chen, Ming-Yu; Charvet, S.; Payard, Pierre-Adrien; Perrin, Marie-Eve L.; Vantourout, Julien C.

Angew. Chem. Int. Ed. 2023, 63, 2, e202311165

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