COB

Organic and Bioorganic Chemistry

The team develops research projects aiming at designing innovative synthetic tools and molecular architectures, based on expertise in homogeneous catalysis, carbohydrate chemistry and heterocyclic chemistry. Projects are conducted within national and international academic or industrial collaborations and partnerships with applications to :

  • biobased and sustainable chemistry
  • synthetic methodology and catalysis *
  • the interface of life sciences.

 

biobased and sustainable chemistry,

recent projects concern the chemistry of furanic platform molecules, aiming at diversifying the molecular design of biobased chemicals while overcoming reactivity and selectivity issues.

synthetic methodology and catalysis,

the projects aims at developing synthetic methodology towards molecules of biological relevance as well as innovation towards biobased chemicals (N or C borrowing hydrogen). Applications range from low- or medium-added value products such as surfactants or polymers, to more elaborated systems such as organocatalysts or molecular scaffolds for fine chemistry.

interface of life sciences,

the team is involved in methodological explorations of biomolecular interactions (carbohydrates, lipids and heterocycles) at the synthetic and physico-chemical level and in projects aiming at the rational design of biologically relevant targets including probes dedicated to the study of biological and biochemical mechanisms and biologically active molecules with antibacterial, pesticide, rodenticide activities.

Our team

forme_membres_ICBMS Mohammed AHMAR

Mohammed AHMAR

CNRS Researcher

forme_membres_ICBMS Thibaut BARBIER

Thibaut BARBIER

PhD student

forme_membres_ICBMS Stéphane CHAMBERT

Stéphane CHAMBERT

Assistant Professor INSA Lyon

forme_membres_ICBMS Jordan FRANCOIS

Jordan FRANCOIS

PhD student

forme_membres_ICBMS Lucie GRAND

Lucie GRAND

Engineering and technical Officer

forme_membres_ICBMS Maïwenn JACOLOT

Maïwenn JACOLOT

forme_membres_ICBMS Jingjing JIANG

Jingjing JIANG

PhD student

forme_membres_ICBMS Malvina LARDUINAT

Malvina LARDUINAT

PhD student

forme_membres_ICBMS Sylvie MOEBS-SANCHEZ

Sylvie MOEBS-SANCHEZ

Assistant Professor INSA Lyon

forme_membres_ICBMS Alexia MOULIN

Alexia MOULIN

forme_membres_ICBMS Pauline PACQUET

Pauline PACQUET

Post-doc

forme_membres_ICBMS Flavien PONSOT

Flavien PONSOT

Post-doc

forme_membres_ICBMS Florence POPOWYCZ

Florence POPOWYCZ

forme_membres_ICBMS Yves QUENEAU

Yves QUENEAU

CNRS Research Director

forme_membres_ICBMS Laurent SOULERE

Laurent SOULERE

Assistant Peofessor with Habilitation

Publications Find the most recent scientific contributions

Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System

Julie Carrard , Fiona Ratajczak , Joséphine Elsens , Catherine Leroy , Rebekah Kong , Lucie Geoffroy , Arnaud Comte , Guy Fournet , Benoît Joseph , Xiubin Li , Sylvie Moebs-Sanchez, Fabrice Lejeune

Biomedicines 2023, 11(10), 2801

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Ir–Na cooperativity controls the diastereoselectivity of borrowing hydrogen C–C alkylation on isosorbide: synthesis methodology and mechanistic investigation

Jordan François, Jordan Rio, Erwann Jeanneau, Marie-Ève L. Perrin, Maïwenn Jacolot, Pierre-Adrien Payard and Florence Popowycz

DOI 10.1039/D3QO00700F

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Synthesis of phospholipids under plausible prebiotic conditions and analogies with phospholipid biochemistry for origin of life studies

Michele Fiore,* Carolina Chieffo, Augustin Lopez, Dimitri Fayolle, Johal Ruiz, Laurent Soulère, Philippe Oger, Emiliano Altamura, Florence Popowycz, René Buchet

Astrobiology 2022, 22, 598–627

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N,N’-alkylated Imidazolium-Derivatives Act as Quorum-Sensing Inhibitors Targeting the Pectobacterium atrosepticum-Induced Symptoms on Potato Tubers

Raoul des Essarts, Y.; Sabbah, M.; Comte, A.; Soulère, L.; Queneau, Y.; Hélias, V.; Faure, F.

Int. J. Mol. Sci. 2013, 14, 19976-19986

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