Research areaChemistry at the interface with Biology and Medicine
Some of the ICBMS teams work at the interface between chemistry and life sciences. Their applications are related to medicinal chemistry, particularly in the field of infectiology, oncology and medical imaging, or aspects aimed at a better understanding of biochemical processes such as membrane properties and cell functions, metabolic processes, but also prebiotic chemistry, self-evolving chemical systems and the development of synthetic vaccines based on glycolipid vesicles. To achieve this objective, the researchers use their expertise to develop various innovative tools as well as cross and multidisciplinary approaches, combining theory and experiments, biomimetic systems, molecular probes and selective enzyme inhibitors.
Research topics ICBMS expertises
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Publications Find the most recent scientific contributions
Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties
Clémence Bonnefoy, Adrien Gallego, Clément Delobel, Betty Raynal, Maxime Decourt, Emmanuel Chefdeville, Gilles Hanquet, Armen Panossian, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard
Eur. J. Org. Chem. 2024, 27, e202400142
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Machine learning approaches for the identification of ligands of the autophagy marker LC3
Laurent Soulère, Yves Queneau
Artificial Intelligence Chemistry 1(2) (2023) 100022
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Importance of the 2,6-Difluorobenzamide Motif for FtsZ Allosteric Inhibition: Insights from Conformational Analysis, Molecular Docking and Structural Modifications
T. Barbier, O. Dumitrescu, G. Lina, Y. Queneau, L. Soulère
Molecules, 2023, 28(5), 2055
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Access to Saturated Aza-Heterocycles using the Borrowing Hydrogen Methodology
Maïwenn Jacolot; Florence Popowycz
https://doi.org/10.1002/ejoc.202301119
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Herbicide detection: A review of enzyme- and cell-based biosensors
Octobre G., Delprat N., Doumèche B., Leca-Bouvier B.