Research areaChemistry at the interface with Biology and Medicine

Some of the ICBMS teams work at the interface between chemistry and life sciences. Their applications are related to medicinal chemistry, particularly in the field of infectiology, oncology and medical imaging, or aspects aimed at a better understanding of biochemical processes such as membrane properties and cell functions, metabolic processes, but also prebiotic chemistry, self-evolving chemical systems and the development of synthetic vaccines based on glycolipid vesicles. To achieve this objective, the researchers use their expertise to develop various innovative tools as well as cross and multidisciplinary approaches, combining theory and experiments, biomimetic systems, molecular probes and selective enzyme inhibitors.

Research topics ICBMS expertises

Chimie médicinale

Chemistry at the interface with Biology and Medicine

Chimiothérapies tropicales

Chemistry at the interface with Biology and Medicine

Glycochimie

Chemistry at the interface with Biology and Medicine

Chimie supramoléculaire

Chemistry at the interface with Biology and Medicine

SysChem: Complex prebiotic and biomolecular systems

Chemistry at the interface with Biology and Medicine

Imagerie

Chemistry at the interface with Biology and Medicine

Membranes biologiques

Chemistry at the interface with Biology and Medicine

Publications Find the most recent scientific contributions

Space radiation damage rescued by inhibition of key spaceflight associated miRNAs

J. Tyson McDonald, Jang Keun Kim,Lily Farmerie,Meghan L. Johnson, Nidia S. Trovao, Shehbeel Arif, Keith Siew, Sergey Tsoy, Yaron Bram, Jiwoon Park,EliahOverbey,Krista Ryon, Jeffrey Haltom, Urminder Singh, Francisco J. Enguita, Victoria Zaksas, Joseph W. Guarnieri, Michael Topper, Douglas C. Wallace, Cem Meydan, Stephen Baylin, Robert Meller, Masafumi Muratani, D.Marshall Porterfield, Brett Kaufman, Marcelo A. Mori, Stephen B. Walsh, Dominique Sigaudo-Roussel, Saida Mebarek, Massimo Bottini, Christophe A. Marquette, Eve Syrkin Wurtele, Robert E. Schwartz, DiegoGaleano, Christopher E. Mason, Peter Grabham & Afshin Beheshti

Nat. Commun. 2024, 15: 4825

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Convergent synthesis of N-(4-(3-ethoxy-2-hydroxypropyl)phenyl)-2-(methylthio) acetamide precursor of the suplatast tosylate

Margherita Colombo, Yousef Joqmara, Guillaume Pilet, Michele Fiore

Trends in Organic Chemistry, 2024, 24, 79-92

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Biochemical, Bioinformatic, and Structural Comparisons of Transketolases and Position of Human Transketolase in the Enzyme Evolution

Biochemistry, 2024

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Confined bioprinting and culture in inflatable bioreactor for the sterile bioproduction of tissues and organs

Scientific Reports 2024, 14: 11003

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The Use of 5-Hydroxymethylfurfural (5-HMF) in Multi- Component Hantzsch Dihydropyridine Synthesis

Jingjing Jiang, Yves Queneau, Florence Popowycz

ChemSusChem 2024, e202301782

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