Research areaOrganic Synthetic Method

Organic Synthetic Method at ICBMS focuses on the development of chemical transformations to either access molecules with targeted applications or to devellop inovative synthetic methods using rational approaches and designs. Our expertise include total synthesis, metal-based catalysis, fluorine chemistry, organo-catalysis, photo-redox and electro-chemistries, mechanistic investigation, modelling and applied theoretical chemistry and found applications in supramolecular chemistry, small molecule activation, biomass valorization, sensors and drug synthesis.

Research topics ICBMS expertises

Catalysis

Organic Synthetic Method

Mechanism / Reactivity

Organic Synthetic Method

Fluorine Chemistry

Organic Synthetic Method

Synthesis and Methodology applied to biomolecules

Organic Synthetic Method

Photochemistry, Electrochemistry

Organic Synthetic Method

Publications Find the most recent scientific contributions

Convergent synthesis of N-(4-(3-ethoxy-2-hydroxypropyl)phenyl)-2-(methylthio) acetamide precursor of the suplatast tosylate

Margherita Colombo, Yousef Joqmara, Guillaume Pilet, Michele Fiore

Trends in Organic Chemistry, 2024, 24, 79-92

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The Use of 5-Hydroxymethylfurfural (5-HMF) in Multi- Component Hantzsch Dihydropyridine Synthesis

Jingjing Jiang, Yves Queneau, Florence Popowycz

ChemSusChem 2024, e202301782

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Hydride-free reduction of propargyl electrophiles: A nickel-catalyzed photoredox strategy for allene synthesis

Hu, Tingjun; Fagué, Vincent; Bouyssi, Didier; Monteiro, Nuno; Amgoune, Abderrahmane

Green Chem, 2024, Accepted Manuscript

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Stereodivergent, kinetically controlled isomerization of terminal alkenes via nickel catalysis.

Rubel, Camille Z.; Ravn,  Anne K.; Ho, Hang Chi; Yang, Shenghua; Li, Zi-Qi; Engle, Keary Mark; Vantourout, Julien C.

Angew. Chem. Int. Ed. 2024, e202320081

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Importance of the 2,6-Difluorobenzamide Motif for FtsZ Allosteric Inhibition: Insights from Conformational Analysis, Molecular Docking and Structural Modifications

T. Barbier, O. Dumitrescu, G. Lina, Y. Queneau, L. Soulère

Molecules, 2023, 28(5), 2055

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