Total synthesis of a target molecule with most often interesting or even unique biological properties represents a challenge to demonstrate the applicability of a pre-established methodologies or in contrast the need to develop new processes. In the two cases, it is a unique opportunity for learning and mastering organic chemistry. The research carried out in the unit is focused on many targets (alkaloids, terpenes, heterocycles, polyketides ...) involving organometallic couplings, organo- and biocatalyzed reactions, multicomponent reactions, electro- and photochemical processes but also the valorization of natural products as highly functionnalized scaffolds.
Rubel, Camille Z.; Cao, Yilin; Ewing, Tamara El-Hayek; Laudadio, Gabriele; Beutner, Gregory L.; Wisniewski, Steven R.; Wu, Xiangyu; Baran, Phil S.; Vantourout, Julien C.; Engle, Keary M.
Fall, I., Doumèche, B., Abdellaoui, S., Rémond C., Rakotoarivonina, H., Ochs M.
A. Loison, G. Hanquet, F. Toulgoat, T. Billard, A. Panossian and F. R. Leroux
Chen, Ming-Yu; Charvet, S.; Payard, Pierre-Adrien; Perrin, Marie-Eve L.; Vantourout, Julien C.