Organic Synthetic MethodSynthesis and Methodology applied to biomolecules
Total synthesis of a target molecule with most often interesting or even unique biological properties represents a challenge to demonstrate the applicability of a pre-established methodologies or in contrast the need to develop new processes. In the two cases, it is a unique opportunity for learning and mastering organic chemistry. The research carried out in the unit is focused on many targets (alkaloids, terpenes, heterocycles, polyketides ...) involving organometallic couplings, organo- and biocatalyzed reactions, multicomponent reactions, electro- and photochemical processes but also the valorization of natural products as highly functionnalized scaffolds.
Publications Find the most recent scientific contributions
Organozinc reagents and nickel
O. Piva
Organozinc Derivatives and Transition Metal Catalysts: Formation of C-C Bonds by Cross-coupling, Ed. J. Cossy, De Gruyter 2023, pp. 63-116
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Glycosaminoglycans: What Remains To Be Deciphered?
Serge Perez,* Olga Makshakova, Jesus Angulo, Emiliano Bedini, Antonella Bisio, Jose Luis de Paz, Elisa Fadda, Marco Guerrini, Michal Hricovini, Milos Hricovini, Frederique Lisacek, Pedro M. Nieto, Kevin Pagel, Giulia Pairardi, Ralf Richter, Sergey A. Samsonov, Romain A. Vivès, Dragana Nikitovic, and Sylvie Ricard Blum
JACS Au 2023 (ASAP)
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ENGINEERING BRANCHING MORPHOGENESIS USING CELL COMMUNICATION
C. Marquette; C. Devillard
Bioprinting Volume 30, April 2023, e00261
Perfluoroalkyl Selenoxides, Selenones and Selenoximines: General Preparation and Properties
A. de Zordo-Banliat, K. Grollier, N. Vanthuyne, S. Floquet, Th. Billard, G. Dagousset, B. Pégot, E. Magnier