Bio
Thierry Billard obtained an engineer diploma from CPE Lyon and his master degree from University of Lyon. He carried out his Ph.D. on fluorine chemistry with B. Langlois (University of Lyon, France), a postdoctoral research in medicinal chemistry with L. Ghosez (University of Louvain-la-Neuve, Belgium) and has completed an industrial postdoctoral stay (Rhone-Poulenc, now Solvay). Afterwards, he joined CNRS in ICBMS (Lyon), where he was appointed research Director.
Member of the executive committee of the "French Fluorine Network"
Member of the scientific committee of the international Prize Henri Moissan
Research interests
His research activities are interdisciplinary involving chemistry and medicine with a focus on fluorine chemistry, medicinal chemistry, radiochemistry and their applications in medical imaging and neurosciences.
Member of GIS-Fluor
Selected publications
Study of Carbamoyl Fluoride: Synthesis, Properties and Applications. C. Bonnefoy, E. Chefdeville, C. Tourvieille, A. Panossian, G. Hanquet, F. Leroux, F. Toulgoat, T. Billard, Chem. Eur. J. 2022, 28, e202201589.
Aromatic Trifluoromethylselenolation via Pd-catalyzed C−H functionalization. K. Grollier, E. Chefdeville, E. Jeanneau, T. Billard, Chem. Eur. J. 2021, 27, 12910-12916.
Study of a Stable “Trifluoromethoxide Anion Solution” Arising from 2,4-Dinitro-Trifluoromethoxybenzene. C. Bonnefoy, E. Chefdeville, A. Panossian, G. Hanquet, F. R. Leroux, F. Toulgoat, T. Billard, Chem. Eur. J. 2021, 27, 15986-15991.
Direct Electrophilic (Benzenesulfonyl)Difluoromethylthiolation with a Shelf-Stable Reagent. E. Ismalaj, D. Le Bars, T. Billard, Angew. Chem. Int. Ed. 2016, 55, 4790-4793.
Publications Find the most recent scientific contributions
Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties
Clémence Bonnefoy, Adrien Gallego, Clément Delobel, Betty Raynal, Maxime Decourt, Emmanuel Chefdeville, Gilles Hanquet, Armen Panossian, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard
Eur. J. Org. Chem. 2024, 27, e202400142
Read the whole publication
SB-258585 reduces food motivation while blocking 5-HT6 receptors in the non-human primate striatum
M. Pitoy, L. Gauthier, J. Debatisse, J. Maulavé, E. Météreau, M. Beaudoin, K. Portier, V. Sgambato, T. Billard, L. Zimmer, S. Lancelot, L. Tremblay
Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2024, 131, 110970
Read the whole publication
Difluoromethoxylated Ketones as Building Blocks for the Synthesis of Challenging OCF2H-Bearing N-Heterocycles
A. Loison, G. Hanquet, F. Toulgoat, T. Billard, A. Panossian and F. R. Leroux
Eur. J. Org. Chem. 2023, 26, e202300695
Read the whole publication
Comprehensive Study and Development of a Metal-Free and Mild Nucleophilic Trifluoromethoxylation.
Clémence Bonnefoy, Armen Panossian, Gilles Hanquet, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard
Chem. Eur. J. 2023, 29, e202301513
Read the whole publication
Perfluoroalkyl Selenoxides, Selenones and Selenoximines: General Preparation and Properties
A. de Zordo-Banliat, K. Grollier, N. Vanthuyne, S. Floquet, Th. Billard, G. Dagousset, B. Pégot, E. Magnier