Prof David GUEYRARD
Professor, LCO2 team leader
david.gueyrard@univ-lyon1.fr
04.72.43.15.57
About David
David Gueyrard was born in Bobigny (France) in 1974. He received his Ph.D. degree (2000) from the University of Orléans under the supervision of Prof. P. Rollin on the synthesis of natural and synthetic glucosinolates. After his Ph.D., he was appointed as a postdoctoral researcher with Prof. C. M. Marson at University College London working on the stereoselective synthesis of organofluorine compounds, before returning to the University of Orléans to join the group led by Prof O. R. Martin and Dr. P. Compain to work on the synthesis of iminosugars. A year later, he moved to the University of Rennes 1 to work on the preparation of synthetic models of cytochrome C oxidase in the group of Dr. B. Boitrel. In September 2003, he was appointed as a Lecturer at the University Claude Bernard Lyon 1 and became Reader in 2008. His research interests consist of the development of new synthetic methodologies to prepare carbohydrate mimics, the extension of the modified Julia olefination on carboxylic acid derivatives and its application in total synthesis.
Recent articles
L. Mologni*, A. Orsato, A. Zambon, S. Tardy, W. H. Bisson, C. Schneider, M. Ceccon, M. Viltadi, J. D'Attoma, S. Pannilunghi, V. Vece, D. Gueyrard, J. Bertho, L. Scapozza*, P. Goekjian, C. Gambacorti-Passerini: Identification of non-ATP-competitive α-carboline inhibitors of the anaplastic lymphoma kinase, Eur. J. Med. Chem., 2022, 238, 114488.
J. Petrignet, J. Thibonnet, L. Commeiras, D. Gueyrard* : Recent advances in the preparation of 3-alkylidenephthalides, Eur. J. Org. Chem., 2022, e202200344.
L. Mologni*, S. Tardy, A. Zambon, A. Orsato, C. Schneider, W. H. Bisson, M. Ceccon, M. Viltadi, D. Goyard, P. Garcia, J. D’Attoma, S. Pannilunghi, V. Vece, J. Bertho, D. Gueyrard, P. Goekjian, L. Scapozza*, C. Gambacorti-Passerini: Discovery of Novel α-Carboline Inhibitors of the Anaplastic Lymphoma Kinase, ACS Omega, 2022, 7, 17083−17097 and ACS Omega, 2022, 7, 22059-22060.
B. Raison, N. Dussart, D. Gueyrard*: Modified Julia olefination on pyrrolidinone: Application to the total synthesis of indolizidine 209D, Eur. J. Org. Chem., 2022, e202200334.
Publications Find the most recent scientific contributions
Evaluation of Nonnatural L-Iminosugar C,C-Glycosides, a New Class of C-Branched Iminosugars, as Glycosidase Inhibitors
Jérôme Désiré, Zakaria Debbah, David Gueyrard, Jérôme Marrot, Yves Blériot and Atsushi Kato
Carbohydr. Res. 2023, 532, 108903
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Deciphering dynamic combinatorial libraries of glycoclusters with miniaturized weak affinity chromatography coupled with mass spectrometry (nano-FAC-MS)
F. Jeanroy, F. Demontrond, F. X. Vidal, D. Gueyrard, S. Vidal, C. Demesmay, V. Dugas
Analytica Chimica Acta, 2023, 1261, 341227
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An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation
A. Caputo, S. Sartini, E. Levati, I. Minato, G. M. Elisi, A. Di Stasi, C. Guillou, P. G. Goekjian, P. Garcia, D. Gueyrard, S. Bach, A. Comte, S. Ottonello, S. Rivara, B. Montanini*
Antibiotics 2022, 11, 1449
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Modified Julia olefination on pyrrolidinone: Application to the total synthesis of indolizidine 209D
B. Raison, N. Dussart, D. Gueyrard*
Eur. J. Org. Chem., 2022, e202200334
Read the whole publication
Identification of non-ATP-competitive α-carboline inhibitors of the anaplastic lymphoma kinase
L. Mologni*, A. Orsato, A. Zambon, S. Tardy, W. H. Bisson, C. Schneider, M. Ceccon, M. Viltadi, J. D'Attoma, S. Pannilunghi, V. Vece, D. Gueyrard, J. Bertho, L. Scapozza*, P. Goekjian, C. Gambacorti-Passerini